Search results for " PCA"

showing 10 items of 41 documents

Essential oil variability in a collection of Ocimum basilicum L. (basil) cultivars.

2016

Ocimum basilicum L. (Lamiaceae) is an aromatic plant of great tradition in the Mediterranean area. Its economic importance is growing up determining an expansion of cultivation. This paper evaluated the morphological traits, the chemical profiles, and antibacterial activity of 21 cultivars of basil belonging to Ê»Genoveseʼ, Ê»Napoletanoʼ, and Ê»Purple basilʼ types. The cultivars were characterized by different growth rate and morphological traits. The chemical composition of the oils analyzed by GC and GC/MS analysis, supported by the PCA analysis, underlined the strong influence of chemotype. It is noteworthy that estragole, never present in Genovese and purple basil types, occurred in …

0106 biological sciencesfood.ingredientPCA analysisBioengineeringMicrobial Sensitivity TestsBiologyGram-Positive Bacteria01 natural sciencesBiochemistrychemistry.chemical_compoundStructure-Activity Relationship0404 agricultural biotechnologyfoodLinaloolMethyl eugenolOcimum basilicum LBiomorphological characteristicAnti-Bacterial AgentBotanyGram-Negative BacteriaAntibacterial activitiesOils VolatileBiomorphological characteristicsMolecular BiologyEssential-oil constituentChemotypeDose-Response Relationship DrugMicrobial Sensitivity TestChemistry (all)Basilicumfood and beveragesEssential-oil constituents04 agricultural and veterinary sciencesGeneral ChemistryGeneral MedicineOcimumbiology.organism_classification040401 food scienceAnti-Bacterial AgentsEugenolchemistryOcimum basilicumMolecular MedicineAntibacterial activitieEstragoleLamiaceaeAntibacterial activities; Biomorphological characteristics; Essential-oil constituents; Ocimum basilicum L.; PCA analysisPCA analysi010606 plant biology & botany
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Chemical Compositions and Antioxidant Activities of Essential Oils, and Their Combinations, Obtained from Flavedo By-Product of Seven Cultivars of Si…

2022

In this work, seven Citrus aurantium essential oils (EOs) derived from flavedo of cultivars ‘Canaliculata’, ‘Consolei’, ‘Crispifolia’, ‘Fasciata’, ‘Foetifera’, ‘Listata’, and ‘Bizzaria’ were investigated. EOs were also combined in 1:1 (v/v) ratio to identify possible synergism or antagonism of actions. GC-MS analysis was done to investigate Eos’ phytochemical profiles. The antioxidant activity was studied by using a multi-target approach based on FRAP, DPPH, ABTS, and β-carotene bleaching tests. A great difference was observed in EOs’ phytochemical profiles. d-limonene (33.35–89.17%) w…

<i>Citrus aurantium</i>; GC-MS analysis; essential oil combinations; <span style="font-variant: small-caps">d</span>-limonene; PCA analysis; global antioxidant scoreOrganic ChemistryPharmaceutical ScienceGC-MS analysid-limoneneAnalytical Chemistryglobal antioxidant scoreChemistry (miscellaneous)Drug Discoveryessential oil combinationMolecular MedicinePCA analysiPhysical and Theoretical ChemistryCitrus aurantiumMolecules
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Metabolic signatures across the full spectrum of non-alcoholic fatty liver disease.

2022

Funder: European Commission

ALTtype 2 diabetes mellitusROC receiving operator characteristicaspartate aminotransferaseHSDLDL low-density lipoproteinUHPLC ultrahigh-performance liquid chromatographyROCHCCNon-alcoholic steatohepatitisGCPCANASHGastroenterology2-HB 2-hydroxybutanoic acid; 3-HB 3-hydroxybutanoic acid; ALT alanine aminotransferase; AST aspartate aminotransferase; CE cholesterol ester; Cer ceramide; FFA free fatty acid; FLIP Fatty Liver Inhibition of Progression; Fibrosis; GC gas chromatography; HCC hepatocellular carcinoma; HSD honest significant difference; LC lipid cluster; LDL low-density lipoprotein; LM lipid and metabolite; LMC lipid metabolite and clinical variable; LPC lysophosphatidylcholine; Lipidomics; Mass spectrometry; Metabolomics; NAFL non-alcoholic fatty liver; NAFLD non-alcoholic fatty liver disease; NAS NASH activity score; NASH non-alcoholic steatohepatitis; NIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research Network; NRR non-rejection rate; Non-alcoholic steatohepatitis; PC(O) ether PC; PC phosphatidylcholine; PCA principal component analysis; PE phosphatidylethanolamine; QTOFMS quadrupole-time-of-flight mass spectrometry; ROC receiving operator characteristic; SAF steatosis activity and fibrosis; SM sphingomyelin; T2DM type 2 diabetes mellitus; TG triacylglycerol; UHPLC ultrahigh-performance liquid chromatographySAFSAF steatosis activity and fibrosisLM lipid and metabolitehonest significant differenceHSD honest significant differenceTG triacylglycerolnon-rejection ratecholesterol esterPCPEGC gas chromatographyfree fatty acidFLIPNASH non-alcoholic steatohepatitisNIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research NetworkBIOMARKERST2DMPE phosphatidylethanolamineLDLlipidNAFLDFFA free fatty acid2-HBMetabolomicsNAFL non-alcoholic fatty liverLMCphosphatidylcholineScience & TechnologySM sphingomyelinGastroenterology & HepatologyMass spectrometryactivitynutritional and metabolic diseasesT2DM type 2 diabetes mellitusACIDSreceiving operator characteristicdigestive system diseasesquadrupole-time-of-flight mass spectrometryLC lipid clusterlow-density lipoproteinNAS2-HB 2-hydroxybutanoic acidNAS NASH activity scoreQTOFMSether PCNRRSCORING SYSTEMprincipal component analysisgas chromatographyLC2-hydroxybutanoic acidPROGRESSIONAST aspartate aminotransferaseLMPC phosphatidylcholinePC(O)MARKERSUHPLCsteatosisTOOLImmunology and AllergyINSULIN-RESISTANCECerSMFatty Liver Inhibition of Progressionhepatocellular carcinoma2-HB 2-hydroxybutanoic acid NIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research Network NRR non-rejection rate Non-alcoholic steatohepatitis PC(O) ether PC PC phosphatidylcholine PCA principal component analysis PE phosphatidylethanolamine QTOFMS quadrupole-time-of-flight mass spectrometry ROC receiving operator characteristic SAF steatosis activity and fibrosis SM T2DM type 2 diabetes mellitus TG triacylglycerol UHPLC ultrahigh-performance liquid chromatographyultrahigh-performance liquid chromatographyCELPC3-HBNAFLnon-alcoholic fatty liverTGtriacylglycerolNRR non-rejection rateLife Sciences & BiomedicineNAFLD non-alcoholic fatty liver diseaseFLIP Fatty Liver Inhibition of Progressionalanine aminotransferasemetaboliteCer ceramideCE cholesterol estersphingomyelinlysophosphatidylcholineand fibrosisALT alanine aminotransferaseInternal MedicineceramideNational Institute of Digestive Diseases and Kidney NASH Clinical Research NetworkAST3-HB 3-hydroxybutanoic acidQTOFMS quadrupole-time-of-flight mass spectrometryPCA principal component analysisLPC lysophosphatidylcholineHepatologynon-alcoholic fatty liver diseaseand clinical variablePC(O) ether PC3-hydroxybutanoic acidFibrosisNASH activity scoreNIDDK NASH-CRNlipid clusterlipid and metabolitephosphatidylethanolamineLipidomicsLMC lipid metabolite and clinical variableFFAHCC hepatocellular carcinomaJHEP reports : innovation in hepatology
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On application of kernel PCA for generating stimulus features for fMRI during continuous music listening

2017

Abstract Background There has been growing interest towards naturalistic neuroimaging experiments, which deepen our understanding of how human brain processes and integrates incoming streams of multifaceted sensory information, as commonly occurs in real world. Music is a good example of such complex continuous phenomenon. In a few recent fMRI studies examining neural correlates of music in continuous listening settings, multiple perceptual attributes of music stimulus were represented by a set of high-level features, produced as the linear combination of the acoustic descriptors computationally extracted from the stimulus audio. New method fMRI data from naturalistic music listening experi…

AdultMaleComputer scienceCognitive Neurosciencemedia_common.quotation_subjectSpeech recognitionmusiikkiSensory systemStimulus (physiology)ta3112050105 experimental psychologyKernel principal component analysisnaturalistic fMRImusic stimulusYoung Adult03 medical and health sciencestoiminnallinen magneettikuvaus0302 clinical medicineRhythmNeuroimagingPerceptionHumans0501 psychology and cognitive sciencesActive listeningmedia_commonBrain MappingPrincipal Component AnalysisNeural correlates of consciousnessGeneral Neuroscience05 social sciencesfunctional magnetic resonance imaging (fMRI)feature generationkernel PCABrainMagnetic Resonance Imagingta6131Auditory PerceptionFemaleärsykkeetMusic030217 neurology & neurosurgerymusical featuresJournal of Neuroscience Methods
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L’espressione del PCA3 in pazienti a rischio di carcinoma della prostata: uno studio prospettico

2014

Carcinoma della prostata Marcatori PCA3
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A PCA-based clustering algorithm for the identification of stratiform and convective precipitation at the event scale: an application to the sub-hour…

2021

AbstractUnderstanding the structure of precipitation and its separation into stratiform and convective components is still today one of the important and interesting challenges for the scientific community. Despite this interest and the advances made in this field, the classification of rainfall into convective and stratiform components is still today not trivial. This study applies a novel criterion based on a clustering approach to analyze a high temporal resolution precipitation dataset collected for the period 2002–2018 over the Sicily (Italy). Starting from the rainfall events obtained from this dataset, the developed methodology makes it possible to classify the rainfall events into f…

ConvectionEnvironmental Engineering010504 meteorology & atmospheric sciencesFunctional data analysis01 natural sciencesExtreme rainfall Convective and stratiform precipitation Functional data analysis PCA-based clustering analysis010104 statistics & probabilityIdentification (information)HyetographClimatologyTemporal resolutionEnvironmental ChemistryPrecipitation0101 mathematicsSafety Risk Reliability and QualityCluster analysisGeology0105 earth and related environmental sciencesGeneral Environmental ScienceWater Science and TechnologyConvective precipitation
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Multivariate analysis in the identification of biological targets for designed molecular structures: The BIOTA protocol

2013

In this work the new protocol BIOlogical Target Assignation (BIOTA) for the prediction of the biological target from molecular structures is proposed. BIOTA is based on the Principal Components Analysis (PCA) application on a matrix of ligands versus molecular descriptors. The application of BIOTA could allow to hypothesize the mechanism of action of a candidate drug prior to its biological evaluation or to repurpose old drugs. The protocol can be fine-tuned by choosing opportune targets (biological or not) and molecular descriptors, and it can be useful in every fields in with it is possible to collect set of compounds with known properties. The robustness of the protocol depends from diff…

CorrectnessComputational biologyBiologyBioinformaticsMolecular descriptorDrug DiscoveryHumansHSP90 Heat-Shock ProteinsMolecular Targeted TherapyPharmacologyPrincipal Component AnalysisBiological dataintegumentary systemBIOTA protocol Biological target Inhibitors PCA Drugs repurposingfungiOrganic ChemistryDrug RepositioningRobustness (evolution)BiotaGeneral MedicineSettore CHIM/08 - Chimica FarmaceuticaBiological targetSettore CHIM/03 - Chimica Generale E InorganicaMultivariate AnalysisPrincipal component analysisIdentification (biology)
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Sign and Rank Covariance Matrices: Statistical Properties and Application to Principal Components Analysis

2002

In this paper, the estimation of covariance matrices based on multivariate sign and rank vectors is discussed. Equivariance and robustness properties of the sign and rank covariance matrices are described. We show their use for the principal components analysis (PCA) problem. Limiting efficiencies of the estimation procedures for PCA are compared.

Covariance matrixbusiness.industrySparse PCAPattern recognitionCovarianceKernel principal component analysisCorrespondence analysisScatter matrixPrincipal component analysisApplied mathematicsArtificial intelligencebusinessCanonical correlationMathematics
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Core–Shell Nanorod Columnar Array Combined with Gold Nanoplate–Nanosphere Assemblies Enable Powerful In Situ SERS Detection of Bacteria

2016

Development of a label-free ultrasensitive nanosensor for detection of bacteria is presented. Sensitive assay for Gram-positive bacteria was achieved via electrostatic attraction-guided plasmonic bifacial superstructure/bacteria/columnar array assembled in one step. Dynamic optical hotspots were formed in the hybridized nanoassembly under wet-dry critical state amplifying efficiently the weak vibrational modes of three representative food-borne Gram-positive bacteria, that is, Staphylococcus xylosus, Listeria monocytogenes, and Enterococcus faecium. These three bacteria with highly analogous Raman spectra can be effectively differentiated through droplet wet-dry critical SERS approach combi…

In situMaterials scienceGram-positive bacteriata221Nanotechnology02 engineering and technologySpectrum Analysis Raman010402 general chemistry01 natural sciencessymbols.namesakeNanosensorGeneral Materials Scienceta318PlasmonNanotubesbiology3D PCASERSStaphylococcus xylosusGram-positive bacteria021001 nanoscience & nanotechnologybiology.organism_classificationListeria monocytogenesnanoarray0104 chemical sciencessymbolsNanorodGoldsuperstructure0210 nano-technologyRaman spectroscopyNanospheresBacteriaACS Applied Materials and Interfaces
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Composition and variability of the essential oil of the flowers of Lavandula stoechas from various geographical sources

2015

Samples of flowers of wild Lavandula stoechas L. spp. stoechas populations were collected in three areas of Sicily (Italy) and were characterized in agronomic and chemical terms. Essential oil (EO) was extracted by hydrodistillation and analyzed by GC-FID and GC-MS. GC-FID and GC-MS analyses permitted identification of 89 compounds from the EO. The samples were separated into 3 groups using PCA (Principal Component Analysis) statistical method, with reference to the chemical composition of the EO. All three Sicilian populations of lavender were identified as the fenchone chemotype with percentage content ranged between 52.8–71.1%. The population of Partinico showed the highest dry weight o…

LavenderLavandulaPopulationWild populationFlowersPlant ScienceLavandula stoechas L. spp. StoechasChemotypeGas Chromatography-Mass SpectrometryEssential oillaw.inventionchemistry.chemical_compoundChemotype Essential oil Lavandula stoechas L. spp. Stoechas PCA Wild populationDry weightlawDrug DiscoveryOils VolatilePlant OilseducationSicilyEssential oilPharmacologyeducation.field_of_studyPCAbiologyChemotypeGeneral Medicinebiology.organism_classificationFenchoneSettore AGR/02 - Agronomia E Coltivazioni ErbaceeHorticultureLavandulaItalyComplementary and alternative medicinechemistryLavandula stoechas L. spp. Stoechas Wild population Essential oil Chemotype PCA.Lavandula stoechas
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